Dock 3 0 9 X 2

Dock 3 0 9 X 2

Thunderbolt™ 3 Compatibility Ideal for the needs of professionals like designers, engineers and animators that demand high speeds. Plug in your peripherals and monitors to a Thunderbolt 3 compatible dock to take advantage of the protocol's operating speeds of up to 40Gbps. RSHTECH USB 3.0 Hard Drives Docking Station Aluminum RSHTECH USB 3.0 Hard Drives Docking Station Aluminum Multifunction SATA External Dual-Bay Dock for 2.5/3. Max Resolution Support1 5120 x 2880 @ 60 Hz USB Type-A Ports (2) USB 2.0 (3) USB 3.0 –one USB 3.0 port on front with USB PowerShare USB Type-C™ Ports (1) Thunderbolt 3 Port Audio/Headphone (1) Combo / (1) Speaker Output Network Gigabit Ethernet LED Indicators Power Adapter LED / Docking Cable Connector LED / RJ-45 LEDs AC Adapter Options. Pacifist 3 5 6 download free.
Dock 3 0 9 X 284
Dock 3 0 9 X 20
Dock 3 0 9 X 2
DOCK3
Identifiers
AliasesDOCK3, MOCA, PBP, Dock3, dedicator of cytokinesis 3, NEDIDHA
External IDs
Gene location (Human)
Chr.Chromosome 3 (human)[1]
Band3p21.2Start50,674,927 bp[1]
End51,384,198 bp[1]
Gene location (Mouse)
Chr.Chromosome 9 (mouse)[2]
Band9|9 F1Start106,892,825 bp[2]
End107,231,909 bp[2]
Gene ontology
Molecular function•SH3 domain binding
•GO:0001948 protein binding
•guanyl-nucleotide exchange factor activity
•Rac guanyl-nucleotide exchange factor activity
Cellular component•cytoplasm
•cytosol
Biological process•small GTPase mediated signal transduction
•positive regulation of non-membrane spanning protein tyrosine kinase activity
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)
RefSeq (protein)n/a
Location (UCSC)Chr 3: 50.67 – 51.38 MbChr 9: 106.89 – 107.23 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse
Dock3 (Dedicator of cytokinesis 3), also known as MOCA (modifier of cell adhesion) and PBP (presenilin-binding protein), is a large (~180 kDa) protein involved in intracellularsignalling networks.[5] It is a member of the DOCK-B subfamily of the DOCK family of guanine nucleotide exchange factors (GEFs) which function as activators of small G proteins. Dock3 specifically activates the small G protein Rac.
Discovery[edit]Dock3 was originally discovered in a screen for proteins that bind presenilin (a transmembrane protein which is mutated in early onset Alzheimer's disease).[6] Dock3 is specifically expressed in neurones (primarily in the cerebral cortex and hippocampus).
Structure and function[edit]

Lion festival slot. Dock3 is part of a large class of proteins (GEFs) which contribute to cellular signalling events by activating small G proteins. In their resting state G proteins are bound to Guanosine diphosphate (GDP) and their activation requires the dissociation of GDP and binding of guanosine triphosphate (GTP). GEFs activate G proteins by promoting this nucleotide exchange.
Non tracking browser windows. Dock3 exhibits the same domain arrangement as Dock180 (a member of the DOCK-A subfamily and the archetypal member of the DOCK family) and these proteins share a considerable (40%) degree of sequence similarity.[7]
Dock 3 0 9 X 284Regulation[edit]Since Dock3 shares the same domain arrangement as Dock180 it is predicted to have a similar array of binding partners, although this has yet to be demonstrated. It contains an N-terminalSH3 domain, which in Dock180 binds ELMO (a family of adaptor proteins which mediate recruitment and efficient GEF activity of Dock180), and a C-terminalproline-rich region which, in Dock180, binds the adaptor protein CRK.[7][8] Pdf to word converter 6 2 1 pdf.
Downstream signalling[edit]Dock3 GEF activity is directed specifically at Rac1. Dock3 has not been shown to interact with Rac3, another Rac protein which is expressed in neuronal cells, and this may be because Rac3 is primarily located in the perinuclear region. In fact, Rac1 and Rac3 appear to have distinct and antagonistic roles in these cells.[9] Dock3-mediated Rac1 activation promotes reorganisation of the cytoskeleton in SH-SY5Yneuroblastoma cells and primary cortical neurones as well as morphological changes in fibroblasts.[10] It has also been shown to regulate neurite outgrowth and cell-cell adhesion in B103 and PC12 cells.[11]
In neurological disorders[edit]The first indication that Dock3 might be involved in neurological disorders came when Dock3 was shown to bind to presenilin, a transmembrane enzyme involved in the generation of beta amyloid (Aβ),[6] accumulation of which is an important step in the development of Alzheimer's disease. Dock3 has been shown to undergo redistribution and association with neurofibrillary tangles in brain samples from patients with Alzheimer's disease.[12] A mutation in Dock3 was also identified in a family displaying a phenotype resembling attention-deficit hyperactivity disorder (ADHD).[13]
References[edit]^ abcGRCh38: Ensembl release 89: ENSG00000088538 - Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000039716 - Ensembl, May 2017
^'Human PubMed Reference:'. National Center for Biotechnology Information, U.S. National Library of Medicine.
^'Mouse PubMed Reference:'. National Center for Biotechnology Information, U.S. National Library of Medicine.
^'Entrez Gene: DOCK3 dedicator of cytokinesis 3'.
^ abKashiwa A, Yoshida H, Lee S, et al. (July 2000). 'Isolation and characterization of novel presenilin binding protein'. J. Neurochem. 75 (1): 109–16. doi:10.1046/j.1471-4159.2000.0750109.x. PMID10854253. S2CID24838995.
^ abCôté JF, Vuori K (December 2002). 'Identification of an evolutionarily conserved superfamily of DOCK180-related proteins with guanine nucleotide exchange activity'. J. Cell Sci. 115 (Pt 24): 4901–13. doi:10.1242/jcs.00219. PMID12432077.
^Hasegawa H, Kiyokawa E, Tanaka S, et al. (April 1996). 'DOCK180, a major CRK-binding protein, alters cell morphology upon translocation to the cell membrane'. Mol. Cell. Biol. 16 (4): 1770–76. doi:10.1128/mcb.16.4.1770. PMC231163. PMID8657152.
^Hajdo-Milasinović A, Ellenbroek SI, van Es S, et al. (February 2007). 'Rac1 and Rac3 have opposing functions in cell adhesion and differentiation of neuronal cells'. J. Cell Sci. 120 (Pt 4): 555–66. doi:10.1242/jcs.03364. PMID17244648.
^Namekata K, Enokido Y, Iwasawa K, Kimura H (April 2004). 'MOCA induces membrane spreading by activating Rac1'. J. Biol. Chem. 279 (14): 14331–37. doi:10.1074/jbc.M311275200. PMID14718541.
^Chen Q, Chen TJ, Letourneau PC, et al. (January 2005). 'Modifier of cell adhesion regulates N-cadherin-mediated cell-cell adhesion and neurite outgrowth'. J. Neurosci. 25 (2): 281–90. doi:10.1523/JNEUROSCI.3692-04.2005. PMC6725471. PMID15647471.
^Chen Q, Yoshida H, Schubert D, et al. (November 2001). 'Presenilin Binding Protein Is Associated with Neurofibrillary Alterations in Alzheimer's Disease and Stimulates Tau Phosphorylation'. Am. J. Pathol. 159 (5): 1567–602. doi:10.1016/S0002-9440(10)63005-2. PMC1867048. PMID11696419.
^de Silva MG, Elliott K, Dahl HH, et al. (October 2003). 'Disruption of a novel member of a sodium/hydrogen exchanger family and DOCK3 is associated with an attention deficit hyperactivity disorder-like phenotype'. J. Med. Genet. 40 (10): 733–40. doi:10.1136/jmg.40.10.733. PMC1735283. PMID14569117.
Further reading[edit]Côté JF, Vuori K (2007). 'GEF what? Dock180 and related proteins help Rac to polarize cells in new ways'. Trends Cell Biol. 17 (8): 383–93. doi:10.1016/j.tcb.2007.05.001. PMC2887429. PMID17765544.
Meller N, Merlot S, Guda C (2005). 'CZH proteins: a new family of Rho-GEFs'. J. Cell Sci. 118 (Pt 21): 4937–46. doi:10.1242/jcs.02671. PMID16254241.
Côté JF, Vuori K (2006). 'In vitro guanine nucleotide exchange activity of DHR-2/DOCKER/CZH2 domains'. Meth. Enzymol. Methods in Enzymology. 406: 41–57. doi:10.1016/S0076-6879(06)06004-6. ISBN9780121828110. PMID16472648.
Chen Q, Kimura H, Schubert D (2002). 'A novel mechanism for the regulation of amyloid precursor protein metabolism'. J. Cell Biol. 158 (1): 79–89. doi:10.1083/jcb.200110151. PMC2173011. PMID12093789.
Brion JP, Anderton BH, Authelet M, et al. (2001). 'Neurofibrillary tangles and tau phosphorylation'(PDF). Biochem. Soc. Symp. 67 (67): 81–88. doi:10.1042/bss0670081. PMID11447842.
Kim JM, Lee KH, Jeon YJ, et al. (2007). 'Identification of genes related to Parkinson's disease using expressed sequence tags'. DNA Res. 13 (6): 275–86. doi:10.1093/dnares/dsl016. PMID17213182.

Retrieved from 'https://en.wikipedia.org/w/index.php?title=Dock3&oldid=982932419'
AKiTiO Thunder2 Dock

Lion festival slot. Dock3 is part of a large class of proteins (GEFs) which contribute to cellular signalling events by activating small G proteins. In their resting state G proteins are bound to Guanosine diphosphate (GDP) and their activation requires the dissociation of GDP and binding of guanosine triphosphate (GTP). GEFs activate G proteins by promoting this nucleotide exchange.
Non tracking browser windows. Dock3 exhibits the same domain arrangement as Dock180 (a member of the DOCK-A subfamily and the archetypal member of the DOCK family) and these proteins share a considerable (40%) degree of sequence similarity.[7]
Dock 3 0 9 X 284Regulation[edit]Since Dock3 shares the same domain arrangement as Dock180 it is predicted to have a similar array of binding partners, although this has yet to be demonstrated. It contains an N-terminalSH3 domain, which in Dock180 binds ELMO (a family of adaptor proteins which mediate recruitment and efficient GEF activity of Dock180), and a C-terminalproline-rich region which, in Dock180, binds the adaptor protein CRK.[7][8] Pdf to word converter 6 2 1 pdf.
Downstream signalling[edit]Dock3 GEF activity is directed specifically at Rac1. Dock3 has not been shown to interact with Rac3, another Rac protein which is expressed in neuronal cells, and this may be because Rac3 is primarily located in the perinuclear region. In fact, Rac1 and Rac3 appear to have distinct and antagonistic roles in these cells.[9] Dock3-mediated Rac1 activation promotes reorganisation of the cytoskeleton in SH-SY5Yneuroblastoma cells and primary cortical neurones as well as morphological changes in fibroblasts.[10] It has also been shown to regulate neurite outgrowth and cell-cell adhesion in B103 and PC12 cells.[11]
In neurological disorders[edit]The first indication that Dock3 might be involved in neurological disorders came when Dock3 was shown to bind to presenilin, a transmembrane enzyme involved in the generation of beta amyloid (Aβ),[6] accumulation of which is an important step in the development of Alzheimer's disease. Dock3 has been shown to undergo redistribution and association with neurofibrillary tangles in brain samples from patients with Alzheimer's disease.[12] A mutation in Dock3 was also identified in a family displaying a phenotype resembling attention-deficit hyperactivity disorder (ADHD).[13]
References[edit]^ abcGRCh38: Ensembl release 89: ENSG00000088538 - Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000039716 - Ensembl, May 2017
^'Human PubMed Reference:'. National Center for Biotechnology Information, U.S. National Library of Medicine.
^'Mouse PubMed Reference:'. National Center for Biotechnology Information, U.S. National Library of Medicine.
^'Entrez Gene: DOCK3 dedicator of cytokinesis 3'.
^ abKashiwa A, Yoshida H, Lee S, et al. (July 2000). 'Isolation and characterization of novel presenilin binding protein'. J. Neurochem. 75 (1): 109–16. doi:10.1046/j.1471-4159.2000.0750109.x. PMID10854253. S2CID24838995.
^ abCôté JF, Vuori K (December 2002). 'Identification of an evolutionarily conserved superfamily of DOCK180-related proteins with guanine nucleotide exchange activity'. J. Cell Sci. 115 (Pt 24): 4901–13. doi:10.1242/jcs.00219. PMID12432077.
^Hasegawa H, Kiyokawa E, Tanaka S, et al. (April 1996). 'DOCK180, a major CRK-binding protein, alters cell morphology upon translocation to the cell membrane'. Mol. Cell. Biol. 16 (4): 1770–76. doi:10.1128/mcb.16.4.1770. PMC231163. PMID8657152.
^Hajdo-Milasinović A, Ellenbroek SI, van Es S, et al. (February 2007). 'Rac1 and Rac3 have opposing functions in cell adhesion and differentiation of neuronal cells'. J. Cell Sci. 120 (Pt 4): 555–66. doi:10.1242/jcs.03364. PMID17244648.
^Namekata K, Enokido Y, Iwasawa K, Kimura H (April 2004). 'MOCA induces membrane spreading by activating Rac1'. J. Biol. Chem. 279 (14): 14331–37. doi:10.1074/jbc.M311275200. PMID14718541.
^Chen Q, Chen TJ, Letourneau PC, et al. (January 2005). 'Modifier of cell adhesion regulates N-cadherin-mediated cell-cell adhesion and neurite outgrowth'. J. Neurosci. 25 (2): 281–90. doi:10.1523/JNEUROSCI.3692-04.2005. PMC6725471. PMID15647471.
^Chen Q, Yoshida H, Schubert D, et al. (November 2001). 'Presenilin Binding Protein Is Associated with Neurofibrillary Alterations in Alzheimer's Disease and Stimulates Tau Phosphorylation'. Am. J. Pathol. 159 (5): 1567–602. doi:10.1016/S0002-9440(10)63005-2. PMC1867048. PMID11696419.
^de Silva MG, Elliott K, Dahl HH, et al. (October 2003). 'Disruption of a novel member of a sodium/hydrogen exchanger family and DOCK3 is associated with an attention deficit hyperactivity disorder-like phenotype'. J. Med. Genet. 40 (10): 733–40. doi:10.1136/jmg.40.10.733. PMC1735283. PMID14569117.
Further reading[edit]Côté JF, Vuori K (2007). 'GEF what? Dock180 and related proteins help Rac to polarize cells in new ways'. Trends Cell Biol. 17 (8): 383–93. doi:10.1016/j.tcb.2007.05.001. PMC2887429. PMID17765544.
Meller N, Merlot S, Guda C (2005). 'CZH proteins: a new family of Rho-GEFs'. J. Cell Sci. 118 (Pt 21): 4937–46. doi:10.1242/jcs.02671. PMID16254241.
Côté JF, Vuori K (2006). 'In vitro guanine nucleotide exchange activity of DHR-2/DOCKER/CZH2 domains'. Meth. Enzymol. Methods in Enzymology. 406: 41–57. doi:10.1016/S0076-6879(06)06004-6. ISBN9780121828110. PMID16472648.
Chen Q, Kimura H, Schubert D (2002). 'A novel mechanism for the regulation of amyloid precursor protein metabolism'. J. Cell Biol. 158 (1): 79–89. doi:10.1083/jcb.200110151. PMC2173011. PMID12093789.
Brion JP, Anderton BH, Authelet M, et al. (2001). 'Neurofibrillary tangles and tau phosphorylation'(PDF). Biochem. Soc. Symp. 67 (67): 81–88. doi:10.1042/bss0670081. PMID11447842.
Kim JM, Lee KH, Jeon YJ, et al. (2007). 'Identification of genes related to Parkinson's disease using expressed sequence tags'. DNA Res. 13 (6): 275–86. doi:10.1093/dnares/dsl016. PMID17213182.

Retrieved from 'https://en.wikipedia.org/w/index.php?title=Dock3&oldid=982932419'
AKiTiO Thunder2 DockThe Thunderbolt™ dock links past, present and future technology to your computer with just one Thunderbolt™ cable. The Thunder2 Dock allows you to access your data on both legacy and future storage drives by providing multiple host ports for USB 3.0, eSATA and FireWire 800. It also has two Thunderbolt 2 ports for daisy chaining additional Thunderbolt devices and storage.
 Features Two Thunderbolt 2 ports for lightning fast speeds up to 20Gb/s
Daisy chain up to 6 Thunderbolt devices
Two eSATA host ports (up to 6Gb/s)
One 7 watt bus-powered FireWire 800 host port
Two bus-powered USB 3.0 host ports (supports UASP)
Durable and rugged aluminum casing
Supports 4K monitors and displays
Linking past, present and future technologyUSB 3.0 supporting UASPFree famly guy games. The two USB 3.0 ports both support UASP (USB attached SCSI protocol) for increased performance over USB 3.0 but the same ports can of course also be used to connect the older USB 2.0 storage drives. Note: The maximum transfer rate for the USB interface is about 370MB/s.
FireWire with bus-power (7W)Long a favorite of Mac users but now replaced by Thunderbolt and USB 3.0, the FireWire interface can still be used through the AKiTiO Thunder Dock. Simply hook up your legacy FireWire drives (bus-powered and self-powered) to the dock and you can access all your existing data without having to buy new hard drive enclosures.
eSATA storage (6Gbps)Dock 3 0 9 X 20Not as common as the other interfaces but PC users will be happy to know that there are also two eSATA ports available to hook up external eSATA drives.
High-Speed I/O PerformanceThunderbolt™ I/OThunderbolt™ is a revolutionary connection technology that simultaneously supports high-resolution displays and high-performance data devices through a single, compact port. Thunderbolt™ technology gives you two channels on the same connector with 10 Gbps of throughput in both directions. The extremely fast and flexible Thunderbolt 2 connection now pushes that to 20 Gbps but the two generations of Thunderbolt technology are compatible with each other. In comparison, it is up to 20 times faster than USB 2.0 and up to 12 times faster than FireWire 800.
Thunder DockOne Thunderbolt™ cable to connect them all. Simply connect the dock to your computer with just one cable and get instant access to all the additional storage drives that are hooked up to the dock. The lighting fast Thunderbolt interface guarantees that you can achieve the best possible data transfer rates.
Thunderbolt™ Daisy ChainStorage & 4K DisplayThe second Thunderbolt port allows you to connect up to 5 additional Thunderbolt devices (storage or display) in a daisy chain. Thunderbolt 2 also has more than enough bandwidth to daisy chain multiple high-speed devices and it gives you access to the latest 4K monitors.
eSATAIndependent eSATA controllersTwo independent eSATA controllers guarantee that the performance doesn't drop, even when a second eSATA storage device is connected at the same time. Please note that the maximum transfer rate for each eSATA port is about 370MB/s.
USB charger (2.1A)Recharge mobile phones & tabletsThe USB ports can be used to recharge your electronic devices (e.g. iPad or iPhone) over USB on Mac OS X 10.9.2 or above (driver installation is required). Providing up to 2.1A, the AKiTiO Thunder Dock can even recharge your larger devices such as the iPad. It also provides power for the Apple Keyboard and the Apple SuperDrive for computers that do not have a built-in SuperDrive.
Model AKiTiO Thunder2 Dock 
Part No.
T2D-THSB3IAS-AKTU

T2D+T3T (with T3T adapter for Thunderbolt 3 computers)

Certifications
CE

FCC

VCCI

Thunderbolt

Warranty
2-year limited warranty

Case material
High quality aluminum

Interface/Ports
2x Thunderbolt 2 ports

2x eSATA host ports (supports port multiplier)

2x USB 3.0 SuperSpeed host ports (supports UASP)

1x FireWire 800 host port (supports bus-power)

Data transfer
Thunderbolt up to 20Gbps

eSATA up to 6Gbps

USB 3.0 up to 5Gbps

FireWire 800 (1394b) up to 800Mbps

System requirements (PC)Not supported
System requirements (Mac)
Mac OS X v10.9 or later

Computer with Thunderbolt™ connector

System environment
Operating Temperature: 5°C ~ 35°C

Storage Temperature: -20°C ~ 60°C

Relative Humidity: 5% ~ 95% (non-condensing)

Power supply
External power supply (UL, cUL, CE, TUV approved)

Input: AC 100-240V

Output: DC +12V/5A

Dimensions (LxWxH)
6.25 inches x 3.83 inches x 0.71 inches

15.88cm x 9.75cm x 1.8cm

Package contents
AKiTiO Thunder2 Dock

Thunderbolt cable

Power adapter

Setup guide

Carton/Packing
Retail Box Size: 9.17 x 7.2 x 3.54 in. (23.3 x 18.3 x 9 cm)

Carton Size (10pcs per carton): 18.9 x 15.4 x 10.04 in. (48 x 39.1 x 25.5 cm)

Gross Weight: 10.7 kg (carton)

Remarks
The two generations of Thunderbolt technology are compatible with each other. The ports and cables are identical.

The device has to be connected to the computer via Thunderbolt interface.

This docking station does not have any internal storage. All data is stored on external drives that are connected to the dock.

In order to recharge an iOS device over USB (e.g. iPhone, iPad or iPad mini), the Thunderbolt cable has to be connected to the computer and the system has to be running (S0 or S3). The OS has to be updated to Mac OS 10.9.2 or above and a driver has to be installed.

The maximum transfer rate for each eSATA port and for the USB interface is about 370MB/s.

This Thunderbolt product is not compatible with Apple's Boot Camp.

Thunderbolt cable not included with all models or in all regions.

To connect this device to a Thunderbolt 3 computer, a Thunderbolt 3 to Thunderbolt adapter like the AKiTiO T3T is required.

This product has components or design elements that are patented or patent pending.

Mac Pros and late model MacBook Pro owners with Thunderbolt ports that need a hub for additional connectivity have a new great option. That option is the Thunder2 Dock from AKiTiO. The hub easily fills the need by adding a group of much needed high-powered ports. Gone are the days of having to unplug one device for another. Read More. Beatunes 5 1 1 – organize your music collection pdf.
Chris Rauschnot - MacTrast (April 26, 2016)
The AKiTiO Thunder2 Dock is something I always have. Whether I'm traveling or if I'm at home working, this little dock is always with me. From the packing to the product, Akitio really knows how to make their customers happy. Read More.
Matthew Stolper - Tech Toolbox (March 14, 2016)
AKiTiO's Thunder2 Dock is impressively thin, portable, and made completely from Mac-matching metal. Measuring only 6.2″ by 3.8″ by 0.65″ — around the size of a typical portable hard drive — it's volumetrically the smallest Thunderbolt 2 dock I've tested, and the easiest to throw in a bag. Read More.
Jeremy Horwitz - 9TO5MAC (October 27, 2015)
Akitio's Thunder2 Dock is a distinctive option both because of its thinner, bag-friendly form factor and its heavy focus on data transfers rather than A/V functionality. This isn't necessarily the dock to pick if you want a one-cable connection to both an HDTV and your peripherals, but it's a very streamlined and versatile way of connecting multiple USB, eSATA, FireWire 800 and Thunderbolt devices to a Mac all at once. Read More.
Jeremy Horwitz - 9TO5MAC (June 27, 2015)
The Akitio Thunderdock 2 is a nice small box. It's about the size of a small USB drive, so it has a very small footprint. And this box sports a lot of connections…two Thunderbolt ports for loop through (very important)…two bus powered USB 3 ports (backwards compatible with USB 2 and USB 1), two eSATA ports (up to 6Gbps), and one FW800 port. Read More.
Shane Ross - Little Frog in High Def (June 13, 2015)
With two eSATA ports, a FireWire 800 port and two USB 3 ports (that can charge your iOS device), the Akitio Thunder2 Dock is geared for someone who needs flexibility with attaching storage devices to your Mac. The dock does have two Thunderbolt 2 connectors and you can connect a Thunderbolt or mini DisplayPort display. When you consider the $279 price (Thunderbolt cable included) and the ports, the Akitio dock fills a niche that's different than the other docks. Read More.
Roman Loyola - Macworld (May 25, 2015)
Compatibility
This product is not supported on Boot Camp
This product is not supported on Windows but works with limited functionality (e.g. no hot plug)
This product does not support FirmTek's SeriTek/5PM eSATA hard drive enclosure
This device has to be connected to the computer via Thunderbolt interface
External drives that are connected to the docking station do NOT spin down unless the power to the drive(s) is turned off
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Output +12V/6A (72W)

Model	AKiTiO Thunder2 Dock
Part No.	T2D-THSB3IAS-AKTU T2D+T3T (with T3T adapter for Thunderbolt 3 computers)
Certifications	CE FCC VCCI Thunderbolt
Warranty	2-year limited warranty
Case material	High quality aluminum
Interface/Ports	2x Thunderbolt 2 ports 2x eSATA host ports (supports port multiplier) 2x USB 3.0 SuperSpeed host ports (supports UASP) 1x FireWire 800 host port (supports bus-power)
Data transfer	Thunderbolt up to 20Gbps eSATA up to 6Gbps USB 3.0 up to 5Gbps FireWire 800 (1394b) up to 800Mbps
System requirements (PC)	Not supported
System requirements (Mac)	Mac OS X v10.9 or later Computer with Thunderbolt™ connector
System environment	Operating Temperature: 5°C ~ 35°C Storage Temperature: -20°C ~ 60°C Relative Humidity: 5% ~ 95% (non-condensing)
Power supply	External power supply (UL, cUL, CE, TUV approved) Input: AC 100-240V Output: DC +12V/5A
Dimensions (LxWxH)	6.25 inches x 3.83 inches x 0.71 inches 15.88cm x 9.75cm x 1.8cm
Package contents	AKiTiO Thunder2 Dock Thunderbolt cable Power adapter Setup guide
Carton/Packing	Retail Box Size: 9.17 x 7.2 x 3.54 in. (23.3 x 18.3 x 9 cm) Carton Size (10pcs per carton): 18.9 x 15.4 x 10.04 in. (48 x 39.1 x 25.5 cm) Gross Weight: 10.7 kg (carton)
Remarks	The two generations of Thunderbolt technology are compatible with each other. The ports and cables are identical. The device has to be connected to the computer via Thunderbolt interface. This docking station does not have any internal storage. All data is stored on external drives that are connected to the dock. In order to recharge an iOS device over USB (e.g. iPhone, iPad or iPad mini), the Thunderbolt cable has to be connected to the computer and the system has to be running (S0 or S3). The OS has to be updated to Mac OS 10.9.2 or above and a driver has to be installed. The maximum transfer rate for each eSATA port and for the USB interface is about 370MB/s. This Thunderbolt product is not compatible with Apple's Boot Camp. Thunderbolt cable not included with all models or in all regions. To connect this device to a Thunderbolt 3 computer, a Thunderbolt 3 to Thunderbolt adapter like the AKiTiO T3T is required. This product has components or design elements that are patented or patent pending.